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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTNNB1
All Species:
32.73
Human Site:
S718
Identified Species:
55.38
UniProt:
P35222
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P35222
NP_001091679.1
781
85497
S718
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Chimpanzee
Pan troglodytes
XP_001137676
774
84747
S711
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Rhesus Macaque
Macaca mulatta
XP_001115474
511
55731
E466
L
G
M
D
P
M
M
E
H
E
M
G
G
H
H
Dog
Lupus familis
XP_850439
744
81740
D695
I
N
E
P
Y
A
D
D
M
D
A
T
Y
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q02248
781
85452
S718
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Rat
Rattus norvegicus
Q9WU82
781
85436
S718
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516985
781
85506
S718
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Chicken
Gallus gallus
NP_990412
781
85420
S718
P
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Frog
Xenopus laevis
P26233
781
85431
S718
Q
D
D
S
S
Y
R
S
F
H
A
A
G
Y
G
Zebra Danio
Brachydanio rerio
NP_571134
780
85502
S717
Q
D
D
P
S
Y
R
S
F
H
S
G
G
Y
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P18824
843
91134
A743
H
S
S
H
G
G
R
A
F
H
Q
Q
G
Y
D
Honey Bee
Apis mellifera
XP_391947
811
88602
S740
Q
G
P
P
S
V
H
S
S
H
G
G
R
G
Y
Nematode Worm
Caenorhab. elegans
O44326
678
74493
W633
M
S
G
S
A
A
D
W
Q
R
D
G
L
E
R
Sea Urchin
Strong. purpuratus
NP_001027543
825
89711
G766
Q
P
P
P
T
M
Q
G
Y
H
D
G
T
G
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
65.4
66.4
N.A.
99.8
99.7
N.A.
99.7
99.3
97.4
97.1
N.A.
65.7
67.6
28.5
67.2
Protein Similarity:
100
99
65.4
77.4
N.A.
99.8
99.7
N.A.
99.8
99.6
99
98.9
N.A.
77.2
80.1
46.4
77.7
P-Site Identity:
100
100
13.3
6.6
N.A.
100
100
N.A.
100
93.3
80
100
N.A.
33.3
40
6.6
26.6
P-Site Similarity:
100
100
20
26.6
N.A.
100
100
N.A.
100
93.3
86.6
100
N.A.
40
40
13.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
15
0
8
0
0
15
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
58
58
8
0
0
15
8
0
8
15
0
0
0
8
% D
% Glu:
0
0
8
0
0
0
0
8
0
8
0
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
65
0
0
0
0
0
0
% F
% Gly:
0
15
8
0
8
8
0
8
0
0
8
79
72
15
58
% G
% His:
8
0
0
8
0
0
8
0
8
79
0
0
0
8
8
% H
% Ile:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
8
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% L
% Met:
8
0
8
0
0
15
8
0
8
0
8
0
0
0
0
% M
% Asn:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
8
8
15
72
8
0
0
0
0
0
0
0
0
0
15
% P
% Gln:
65
0
0
0
0
0
8
0
8
0
8
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
65
0
0
8
0
0
8
8
8
% R
% Ser:
0
15
8
15
65
0
0
65
8
0
50
0
0
0
0
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
58
0
0
8
0
0
0
8
65
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _